GLP-1 agonists, like semaglutide and tirzepatide, are groundbreaking treatments for managing type 2 diabetes and obesity. These medications work by mimicking the glucagon-like peptide-1 (GLP-1) hormone, which helps control blood sugar levels and promotes weight loss.
When you embark on a weight loss program at Hopkins MD, we may use GLP-1 agonists to support your journey. We always explain the possible side effects so you can weigh the risks and benefits, and we monitor you closely throughout so we can help if you experience any reactions.
Let’s look at what GLP-1 agonists are, why we use them, and how you can manage side effects.
GLP-1 agonists are medications that lower levels of glucagon (a hormone that raises blood sugar), boost production of the digestive hormone insulin, and slow down how quickly your stomach empties.
These effects help regulate blood sugar and make you feel fuller for longer, resulting in reduced calorie intake and subsequent weight loss. Most of these medications are injections, with dosing schedules that vary depending on the brand and specific treatment plan.
While patients generally tolerate GLP-1 agonists well, some may experience side effects, especially when starting treatment. The most common ones include:
Recognizing these potential side effects can help you manage them effectively.
We recommend the following to help you manage the side effects listed above.
We advise starting slowly, beginning with a low dose and increasing it gradually. This helps your body adjust to the medication and reduces nausea.
Avoid fatty, fried, or spicy foods, which often worsen nausea. Stick to lighter meals that are easier to digest. Gradually increase your fiber intake with whole grains, fruits, and vegetables to keep your bowels moving. If it’s hard to get enough fiber through food, consider supplements — we can recommend some for you.
Regular meals with a good balance of carbs, proteins, and fats help maintain steady blood sugar levels. A temporary liquid diet of protein shakes or blended meals might help if nausea persists.
Regular fluid intake prevents dehydration, reducing the risk of constipation. Dehydration can also make headaches and dizziness worse. Sip water or clear liquids frequently, especially if you’re feeling nauseous, and limit caffeine and alcohol intake because they contribute to dehydration and make headaches worse.
Ginger or peppermint preparations can help settle your stomach, but always check with us before using herbal remedies.
Opt for more frequent meals with smaller portions. Chew your food thoroughly and eat slowly.
Sugar substitutes are often present in foods promoted for weight loss. However, they can cause stomach discomfort, so steer clear of them.
Walking, cycling, swimming, or other regular physical activities promote healthy digestion and regular bowel movements.
Keep glucose tablets, juice, or other quick sugar sources handy in case your blood sugar drops. If you’re on other diabetes medications, we may need to adjust dosages to avoid hypoglycemia (low blood sugar).
Prioritize good sleep with a regular bedtime, and avoid stimulants like caffeine and screen time before bed. Manage stress through relaxation techniques like deep breathing, or take up meditation, yoga, or tai chi.
In addition to managing side effects, lifestyle changes can improve how well GLP-1 agonists work and enhance your overall experience. Consult our wellness coach for tailored guidance on healthy lifestyle changes.
We show you how to inject yourself with GLP-1 and ensure you’re happy with the procedure when you start your weight loss plan. However, injection site reactions can be a problem for some people using GLP-1 agonists.
Follow the injection instructions carefully to minimize irritation, clean the injection site before use, and avoid areas with scars or moles. Don’t use the same spot repeatedly; rotating helps prevent soreness and skin issues. Let us know if you notice significant redness, swelling, or pain.
Managing GLP-1 side effects doesn’t have to be overwhelming. With the right strategies and support from the Hopkins MD team, you can minimize discomfort and focus on the benefits these medications offer.
Don’t hesitate to reach out to us with any concerns — we’re here to help you succeed. Call our offices in Roseville or Lincoln, California, at 916-253-9996, or use the online inquiry form to get in touch.
